The advanced coreg tool provides automatic coregistration using the Mutual Information (MI) similarity measure, together with access to lower-level parameters in the coregistration. Although the MI coregistration can be used by following the instructions below, the other functions available here are only used for research into coregistration. See Tina Memo 2004-001 for more information.
The MI coregistration has been found to give a more accurate determination of the parameters of a coregistration, particularly the rotation parameters. In order to invoke it, load and latch the target volume, then load and roughly align the source image volume, as with the simple coreg tool. Select the choices in the advanced coreg tool as follows: