Detection of MS Lesions in MRI Scans using Non-Parametric Image Subtraction

ISMRM 2002, Honolulu, Hawaii.

MS lesions can be detected by simple subtraction of MRI scans taken before and after the injection of GdDTPA contrast agent. However, this highlights global changes in the post-injection scan in addition to the lesions. We introduce a newnon-parametric subtractionmeasure, analogous to standard statistical tests, which allows a direct probabilistic interpretation of image differences. We demonstrate the technique using scans of MS lesions, but we expect it to be applicable to a wide range of image formation processes.

pab_ismrm2002.pdf (254kB)

pab_ismrm2002_poster.pdf (1384kB). The poster from the conference.